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Glaucoma and Alzheimer's May Have Common Origins and Treatment

LONDON, Aug. 6 -- A combination of drugs that target the amyloid-beta pathway

implicated in Alzheimer's disease appear to be highly effective against glaucoma as well, at least in animal models, investigators here reported.

Amyloid-b peptide, found to accumulate in the brains of people with Alzheimer's disease, accelerated the programmed death of retinal ganglion cells in rat models of glaucoma, but its action was prevented by three drugs that inhibit Ab formation and aggregation, wrote M.


New Techniques Could Spot Alzheimer's Early


MONDAY, June 11 (HealthDay News) -- Three groups of researchers are reporting progress on the early detection of Alzheimer's disease -- advances that, if validated, could aid patients and drug developers alike, experts said.

In one study, a Norwegian team identified a gene expression "signature" that distinguishes people with Alzheimer's from healthy individuals with an up-to-85 percent accuracy.


Women who used estrogen hormone therapy before the age of 65 were less likely to develop Alzheimer's


From Thursday's Globe and Mail

May 3, 2007

Women who used estrogen hormone therapy before the age of 65 were less likely to develop Alzheimer's disease than women who didn't take the hormone, according to data released yesterday.


Reversing Alzheimer's memory loss may be possible

By Will Dunham

Mon Apr 30 2007

WASHINGTON (Reuters) - Mental stimulation and drug treatment may help people with brain ailments such as Alzheimer's disease regain seemingly lost memories, according to research published on Sunday.

Scientists used two methods to reverse memory loss in mice with a condition like Alzheimer's -- placing them in sort of a rodent Disneyland to stimulate their brains, and also using a type of drug that encourages growth of brain nerve cells.


Alzheimer's Memory Loss May One Day Be Reversible

Article Date: 30 Apr 2007

A new US study suggests it may one day be possible to reverse the memory loss associated with Alzheimer's and similar degenerative brain diseases.

The study is published in Nature.

Scientists at MIT's Picower Institute for Learning and Memory in Cambridge, Massachusetts, put mice with induced brain atrophy in an enriched environment; a "playground" where they had the company of other mice, were given new colourful toys to play with every day, and were able to exercise on wheels.


More than 5 million have Alzheimer's in U.S.

Tue Mar 20, 2007

WASHINGTON (Reuters) - More than 5 million people in the United States have Alzheimer's disease and an aging population is likely to fuel a steady rise in new cases, a report released by the Alzheimer's Association said on Tuesday.

The association's figure of 5 million is up about 10 percent from its previous estimate in 2000, and it said there are about 400,000 new cases a year.


Aging Cats Get Alzheimer's Disease, May Help Human Research

By Jason Gale

Dec. 6 (Bloomberg) -- Aging cats who forget their owners, cry out in the night and become confused may be suffering from Alzheimer's disease. New research shows felines can suffer the same memory-robbing illness that causes dementia in humans.

U.K. and U.S. scientists have identified a protein accumulating in the nerve cells of cats' brains causing mental deterioration, they said in an e-mailed statement today. In humans with Alzheimer's, the same protein creates tangles inside nerve cells, inhibiting messages being processed by the brain.


After 100 Years, Alzheimer's Still Somewhat a Mystery


Nov. 3, 2006 —

 If I turned back the clock 100 years to Nov. 3, 1906, and happened to be sitting, surrounded by psychiatrists in a small stone auditorium in the village of Tubingen, Germany, I might see on the program the name of a speaker, Dr. Alois Alzheimer.

Alzheimer actually spoke in this German auditorium in 1906, and he described a patient named "Augusta" who, in her middle 50s, had developed the seemingly unfounded delusion that her husband was unfaithful.