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Cancer

Non-Mutated Breast Cancer Gene Finds, Fixes DNA

Mon Aug 26, 2002

By Linda Carroll

NEW YORK (Reuters Health) - Stanford researchers have discovered the normal function of the BRCA1 gene, the gene that--when mutated--leads to a high risk of breast cancer. According to the new study, the BRCA1 gene normally has the job of finding and repairing damaged DNA.

To test their theory that BRCA1 helps to repair damaged DNA, the researchers tweaked cells to make them overproduce the BRCA1 gene, according to the study, which was published in the advance online edition of Nature Genetics.

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Coffee, Chocolate Compounds Potential Cancer Drug

Wed Aug 21, 2002

By Stephen Pincock

LONDON (Reuters Health) - Compounds found in coffee and chocolate could form the basis of new drugs for cancer, heart disease and inflammation, British scientists said on Wednesday.

Professor Peter Shepherd and colleagues from University College London and elsewhere found that caffeine and a related molecule called theophylline block an enzyme that is crucial for cell growth.

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Scientists Probe Nev. Cancer Cluster

Tue Aug 20, 2002

By BRENDAN RILEY, Associated Press Writer

FALLON, Nev. (AP) - High levels of arsenic and tungsten were found in residents of this northern Nevada town during an investigation of a mysterious cancer cluster, government scientists reported Tuesday.

There's no known correlation, however, between high levels of the minerals and acute lymphocytic leukemia, the Centers for Disease Control and Prevention said. Of the 16 confirmed childhood leukemia victims linked to Fallon since 1997, three have died.

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Report Cites 'Dangerous' Cancer Advice on Web

Tue Aug 20, 2002

By Pat Hagan

LONDON (Reuters Health) - Some Internet sites that promote alternative remedies for cancer are potentially dangerous to patients, according to the results of a new survey.

The study of 13 alternative medicine sites revealed that some discourage patients from using conventional treatments, such as chemotherapy, and instead promote alternative remedies for which there is little or no evidence of effectiveness.

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Breast Cancer Gene May Carry Less Risk Than Thought

Tue Aug 20, 2002

By Merritt McKinney

NEW YORK (Reuters Health) - For women who carry genetic mutations that have been linked to an increased risk of breast cancer , the risk may not be as high as first thought, a new report suggests.

While this may sound like good news to women who carry the BRCA1 or BRCA2 mutations, which have been linked to a 71% to 85% lifetime risk of breast cancer, determining an individual woman's risk remains difficult, according to Dr. Colin B. Begg of Memorial Sloan-Kettering Cancer Center in New York.

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Cancer Gene Uncovered

Wed Aug 14, 2002

WEDNESDAY, Aug. 14 (HealthScoutNews) -- A gene associated with development of melanoma and colon cancer has been identified by scientists at the Weizmann Institute of Science in Israel.

The gene is called Nr-CAM and it normally encodes a Cell Adhesion Molecule (CAM) in neuronal, or nerve cells. However, Dr. Avri Ben-Ze'ev and his colleagues found that when Nr-CAM is expressed at high levels in other types of cells, it can help drive the progression of cancer.

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Cancer Drug May Restore Color to Gray Hair

Thu Aug 8, 2002

BOSTON (Reuters) - A drug normally used to treat an adult form of leukemia may be able to restore color to gray hair, a team of puzzled French doctors reported on Wednesday.

Of the 133 people they treated with the drug, sold under the brand name Gleevec by Swiss drugmaker Novartis AG, five men and four women who started out with gray hair ended up with their old color back.

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Scientists Find New Clues About How Cancer Spreads

Mon Aug 5, 2002

By Patricia Reaney

LONDON (Reuters) - Scientists have discovered how a key protein helps cancerous cells spread through the body in a finding that could pave the way for new drugs to slow the progression of the disease.

The molecule, called Src, loosens the tissue around a tumor and allows cancerous cells to metastasize, or grow in other organs.

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Grouchy? Type A? It Won't Affect Breast Cancer Risk

Fri Aug 2, 2002

By Michelle Rabil

NEW YORK (Reuters Health) - Personality has no effect on breast cancer risk, according to a large study of twins published in the International Journal of Cancer.

While it has been suggested that there may be a cancer-prone personality, study authors report that being extroverted, neurotic or hostile or having a type A personality do not, individually or in combination, increase a woman's risk of developing the disease, which should help ease women's concerns.

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Grouchy? Type A? It Won't Affect Breast Cancer Risk

Fri Aug 2, 2002

By Michelle Rabil
NEW YORK (Reuters Health) - Personality has no effect on breast cancer
risk, according to a large study of twins published in the International Journal
of Cancer.
While it has been suggested that there may be a cancer-prone personality,
study authors report that being extroverted, neurotic or hostile or having a
type A personality do not, individually or in combination, increase a woman's
risk of developing the disease, which should help ease women's concerns.

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