Anti-Cancer Power of Coenzyme Q10,Natural Progesterone and Melatonin
Coenzyme-Q10 (ubiquinone) is a vitamin-like, non-toxic compound that plays a critical role in generating energy within the power plants of our cells (the mitochondria), and is a highly potent antioxidant that counteracts damaging free radical activity.
There is a large (and rapidly growing) body of evidence that supplementation with Co Q10 can protect us against cardiovascular diseases and that Co Q10 is an effective treatment for angina (heart pain), cardiac arrhythmias, and other cardiovascular diseases. Further, Co Q10 has been shown to extend lifespan in laboratory animals.
New Breast Cancer Studies
One of the pioneering scientists in the exploration of the clinical benefits of Co Q10 is Karl Folkers of the Institute for Biomedical Research at the University of Texas in Austin. Dr. Folkers has been conducting Co Q10 research for about 35 years, and has edited several textbooks on the subject.
Recently, Dr. Folkers has been collaborating with Knud Lockwood, Sven
Moesgaard, and other scientists at a Private outpatient clinic in
Copenhagen, Denmark to assess the benefits of Co Q10 in breast cancer
patients, with some truly remarkable results.
In the first study, 32 patients with breast cancer, aged 32-81, who were classified as "high-risk" because their tumors had metastasized to their lymph nodes, were given an "Adjuvant Nutritional Protocol" in addition to standard surgery and chemotherapy for 18 months.
The daily nutrients added to their treatment were: 2,850 mg of vitamin-C, 2,500 mg of vitamin E, 58 mgs of beta-carotene, 387 micrograms of selenium (plus secondary vitamins and minerals), 1.2 gm of gamma linolenic acid, 3.5 grams of n-3 fatty acids, and 90 mg of Co Q10.
The Danish scientists found that:
"Six of the 32 patients showed partial tumor regression, none of the patients died during the study period (the expected number was four), none of the patients showed signs of further distant metastases, and the quality of life was improved (no weight loss, reduced use of pain killers) in all the patients studied. After 24 months, all the patients were still alive."
Raising The Dosage of Co-Q10
The positive results of this study led the scientists to increase the dose of Co Q10 to 390 mg per day in one of the patients, a 59-year-old woman with a family history of breast cancer. This woman had been operated on for removal of a malignant tumor in her left breast in July 1991. Mammography in May 1992 showed tumor tissue remaining in her left breast and other tests revealed metastasized tumor cells in her lymph nodes.
The woman was started on the nutritional regimen described above in October 1991. In October 1993, her daily intake of Co Q10 was raised to 390 mg/day. "In November 1993, the tumor was no longer palpable. Mammography in December 1993 confirmed normal conditions with no signs of the tumor..."
Encouraged by this complete regression of a breast tumor, they began to give 390 mg per day of Co Q10 to a 74-year old woman who had refused further surgery after learning that her breast cancer had not been eradicated by previous surgery. Late in 1993, the patient was given daily doses of 390 mg of Co Q10 and: "On January 25, 1994, clinical examination revealed no evidence of tumor or distant metastases. Mammography revealed no residual tumor. As of February 1994, therapy continues with 300 mg co Q10. Clinical condition is excellent."
Since then, the Danish scientists (and Folkers) have reported the results of treating three additional patients with 390 mg a day of Co Q10 in addition to a conventional protocol. They reported that:
"The numerous metastases in the liver of a 44-year-old patient disappeared, with no signs of metastases found elsewhere. A 49-year-old patient, on a dose of 390 mg of Co Q10, revealed no signs of tumor in the pleural cavity after six months and her condition was excellent. A 75-year-old patient with carcinoma in one breast after lumpectomy showed no cancer in the tumor bed or metastases after receiving 390 mg per day of Co Q10."
Dr. Lockwood is an oncologist (in Denmark) who has been treating 200 cases of breast cancer a year for the past 35 years. He says that he has "never seen a spontaneous complete regression of a 1.5-2.0 cm. breast tumor, and has never seen a comparable regression with any conventional anti-tumor therapy." Dr. Lockwood is amazed at the remarkable anti-cancer power of Coenzyme Q10 and is continuing (with his colleagues) to treat breast cancer patients with 390 mg per day of Co Q1O.
Protection Against Breast Cancer With Co-Q10
Dr. Folkers has found that breast cancer patients have significantly lower blood levels of Co Q10 than normal people. This finding, combined with the remarkable results of treating breast cancer patients with Co Q10 in Denmark, is persuasive evidence that taking supplemental Co Q10 can protect women against breast cancer.
For prevention purposes, we recommend a Co Q10 dose of 100 mg per day. Women who are at high risk for breast cancer because of a family history of the disease, or because they have already had breast cancer, should take 200-300 mg a day of Co Q10.
You can purchase Co Q10 in 100-mg capsules On-Line.
Unlike the synthetic progestins approved by the FDA that may increase your risk of breast cancer, natural progesterone protects against many of estrogen's lethal side effects and protects against osteoporosis better than estrogen. While estrogen protects against osteoporosis by preventing the loss of bone, progesterone can actually reverse the process by increasing bone density. Dr. john Lee has found that the use of a topical progesterone cream leads to a 10% increase in bone density within 6-to-12 months, followed by an annual increase of 3%-to-5% until the bone density of his postmenopausal patients stabilizes at the levels of healthy 35-year-old women!
Several prospective studies have shown a significantly higher incidence of breast cancer in progesterone-deficient women. One study, in which 1,083 women were examined, found that premenopausal women who were deficient in progesterone had a 5.4 times greater risk of breast cancer! Progesterone deficiency can also be a cause of depression, irritability, mood swings, and insomnia.
If you use DHEA or other therapies to boost estrogen levels, than it is even more important for you to apply transdermal natural progesterone cream to your skin on a daily basis.
Premenopausal women can use one-eighth to one quarter-teaspoon of topical natural progesterone cream every day during the 15th to 28th day of their menstrual cycle. Menopausal and postmenopausal women should use a half-teaspoon of natural progesterone cream twice daily for the first month, then reduce the amount to one-quarter of a teaspoon daily.
Progesterone is absorbed through fat cells under the skin. It is, therefore, important to apply topical progesterone cream to different parts of your body every day to avoid saturating your fat cells, thereby inhibiting progesterone absorption.
As with estrogen replacement therapy, it is important to have complete hormone saliva tests on a regular basis to make sure you are getting enough progesterone to block estrogen's carcinogenic effects and to prevent bone loss.
Melatonin, the primary hormone of the pineal gland, acts as a powerful "chronobiotic," maintaining normal circadian rhythms. In patients with sleep disorders and exogenously-generated desynchrony of circadian rhythms such as occurs in jet lag, oral administration of melatonin can provide the necessary resynchronization of those cycles, at dosages ranging from 0.3 to 8 mg.
Synthesis of melatonin from the amino acid tryptophan has been shown to be decreased by exposure to magnetic fields and by the aging process.
Melatonin also possesses potent free radical scavenging properties and has been recognized as exerting direct inhibition of cancer growth. Various cancer types have been shown to be responsive to oral melatonin (10 to 50 mg daily), including breast cancer, non-small-cell lung cancer, metastatic renal cell carcinoma, hepatocellular carcinoma, and brain metastases due to solid tumors. Melatonin has also been reported to lower total cholesterol and LDL levels in rats, and abnormally low melatonin levels have been theorized to be a factor in multiple sclerosis, sudden infant death syndrome, coronary heart disease, epilepsy, and postmenopausal osteoporosis. These reports, while preliminary, serve to further illustrate the wide range of potential effects exerted by melatonin. (Alt Med Rev 1996;1(2):94-102)
AIBMR found four studies reporting that melatonin inhibits cancer of the breast, lung, brain, and prostate. Recent observations have shown that melatonin may modulate estrogen receptor expression and inhibit breast cancer cell growth. Preliminary data suggests that melatonin might enhance the anti-tumor activity of tamoxifen (a drug used to treat breast cancer). In a pilot phase II human study, the administration of 20 mg of melatonin at bedtime taken along with tamoxifen showed tumor regression in women. Another study showed that neuroimmunotherapy with interluekin-2 and melatonin may represent a new effective way to treat metastasis non-small cell lung cancer.
High estrogen levels in both men and women usually lead to cancer or other illnesses often associated with aging, including breast and uterine cancers, and weight gain.
Supplementing the diet with DIM and eating cruciferous vegetables increases the specific aerobic metabolism for estrogen, multiplying the chance for estrogen to be broken down into its beneficial, or "good" estrogen metabolites. These "good"estrogen metabolites are known as the 2-hydroxy estrogens. Many of the benefits that are attributed to estrogen, which include its ability to protect the heart and brain with its antioxidant activity, are now known to come from these "good" metabolites.
When DIM increases the "good" estrogen metabolites, there is a simultaneous reduction in the levels of undesirable or "bad" estrogen metabolites. These include the 16-hydroxy estrogens, which are not antioxidants and can actually cause cancer.
Greater production of these "bad" estrogen metabolites is promoted by obesity and exposure to a number of manmade environmental chemicals. These "bad" estrogen metabolites are responsible for many of estrogen's undesirable actions in women and men, including further unwanted weight gain, breast cancer, uterine cancer, and prostate cancer.
DIM is highly recommended for women on HRT or at risk for breast cancer, as it will reduce the toxic effects to estrogen dominance. "Regarding the ratio of 2-OH-estrone to 16-alpha-estrone, which is newer to me, I can inform you that a poor 2/16 ratio (lower 2OH : higher 16-alpha) has been shown to be carcinogenic. Extracts of cruciferous vegetables such as I3C (indole-3-carbinole) and its more absorbable metabolite DIM (di-indolyl-methane) apparently improve this ratio thru up-regulation of the CYP1A2 liver enzymes involved in the metabolism of estrogens (Cancer Lett 1997;114(1-2):169-170).
Antioxidants prevent cancers of all types by reducing the amount of free radicals produced by the body.
HORMONE REPLACEMENT THERAPY OR HRT IS A MAJOR SOURCE OF CANCERS IN WOMEN OF ALL TYPES.
HRT will be the greatest tragedy of modern medicine. Promoted and approved by the FDA, hyped and advertised by the pharmaceutical giants it has now been declared by the FDA asa major cause of breast and ovarian cancers, endometriosis, weight gain, and a whole panoply of devastating illnesses that has ruined the health and ended the lives of countless women. Please click on the above link for further information on HRT, including information on how you can join a class action lawsuit against the perpetrators of this most cruel of all medical hoaxes.