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Essentials of Natural Chelation


Posted by Mark Sircus - Director on 13 December 2011

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Almost 20 percent of the children in this country are
chronically ill or disabled. That’s a very different situation from
what it was 20 or 30 years ago, and there’s no explanation
given by the public health authorities as to why that is true.
Barbara Loe Fisher
National Vaccine information Center

The pristine environments of the world have vanished, We have now realized too late that the same thing has happened to our bloodstreams, cells and tissues. As the ability of science to measure increasingly smaller amounts of toxins in the body improves, we are finding that it does not take very large amounts to degrade bodily functioning. What’s worse, these many toxins combine in unpredictable ways to produce a combined effect, worse than the sum of the individual effects.

The really bad news is that we have open nuclear wounds on the planet belching out radioactive materials around the entire northern hemisphere, a fact that the entire medical community stubbornly ignores. Medical officials have also kept their mouths shut about the clouds of mercury that have been penetrating every corner of the earth—as well as every cell in our bodies. All the coal fired plants in the world together put out thousands of tons of mercury into the environment and it gets into everything. Modern medicine and dentistry have also contributed to the poisoning of the public by their use of dangerous chemicals, heavy metals and radiation (For more on radiation dangers and treatments see my book Nuclear Toxicity Syndrome and also the second edition of my book Iodine).

Some crazy countries routinely use depleted uranium weapons
on the battlefield and the fallout from
that stuff stays around for a few billion years.

Fortunately for our children and for us there are natural and semi-natural forms of treatment that can reverse much of the damage of mercury, lead, arsenic and other chemical poisoning. Even uranium can be eliminated with the proper protocol.

Chelation has been shown to be effective at removing
plutonium from the most carcinogenic locations in
the skeleton, such as on bone surfaces near living cells.[1]

Dr. Jaquelyn McCandless says, “Oral agents, especially DMSA, can encourage yeast overgrowth.” When chelating people with a heavy metal burden, particularly when they are young children or very elderly or have any chronic disease, it is best to mobilize and eliminate the metals gently, slower rather than faster, so that the body can reabsorb less and avoid flooding the body with toxic metals that cause further oxidative stress due to their free radical activity.

Natural chelators are safe, non-invasive, affordable and available without prescription as they are considered food supplements. In reality there is a tremendous amount of anecdotal evidence with a host of chelation products and substances on the market but very little hard proof. It is far easier to make claims than to prove their efficacy by way of costly clinical studies.

Metal chelation is a complex and serious matter. It is a fact that you can end up in worse health after chelation than when you started if you are not well-informed and do not proceed carefully under the care of a competent healthcare practitioner.

Synthetic chelators can be used to good effect by competent doctors but their dangers are ever present. Some of the more aggressive chelation procedures are appropriate in the cases of acute toxic exposure but even with stage-four cancers or imminent threat of heart attack or stroke it is probably best to use gentle approaches whenever possible.

Mortality from cancer was reduced 90 percent during an 18-year
follow-up of 59 patients treated with calcium-EDTA. Only one of
59 treated patients (1.7 percent) died of cancer while 30 of 172
non-treated control subjects (17.6 percent) died of cancer (P=0.002).[2]
Dr. Walter Blumer

Dr. Garry Gordon, a leader in the field of chelation says, “No one on planet earth is operating at optimal levels without doing something about the toxic metals. Thus the conclusion I draw is that chelation appears to be a lifetime necessity for all. There is no chelation that can dent the lead levels of bones unless continued for at least seven years (bone turnover time).”[3]

So, if you are betting your patients’ health on effective protection, you need to get into chelation and detoxification for the long haul. This is one of the principle reasons we need natural nontoxic substances. Using synthetic drugs with their own toxic side effects is not the best way to chelate.[4] Even EDTA, which is much less toxic than DMPS and DMSA, may not be appropriate for treating low-level lead exposures because it can be toxic in that it also increases excretion of some essential metals. EDTA produces substantial diuresis of zinc and a temporary 30-40 percent decrease in plasma zinc.[5]

Dr. George Georgiou says, “Many health practitioners use synthetic chelating agents such as DMPS, DMSA, EDTA and others to mobilize and eliminate heavy metals from the body. There are advantages and disadvantages to using these. One advantage is the power of their mobilizing activity—they are quick to mobilize and eliminate certain metals in the body, but this may place a huge burden on the body’s detoxification systems. Further symptoms have been reported by natural medical physicians throughout the U.S., such as intractable seizures in pediatric patients and multiple sclerosis in adult patients due to taking high doses of DMSA over extended periods of time. These are valid reasons to be at least cautious in the use of DMSA for the treatment of mercury-toxic pediatric patients. The fragile brains and nervous systems of children with autism, PDD and seizure disorders should be handled with considerable care so as not to increase the damage.”

Chelation therapy was introduced into the United States in 1948.
The treatment is well recognized by doctors around the world.

Heavy Metal Detox

In a large metal foundry in Russia, Dr. George Georgiou tested extensively many natural substances for their efficacy in removing heavy metals from the workers there and found chlorella and cilantro so effective—when used “together”—that he introduced “Heavy Metal Detox” (HMD) in 2005.[6] But the issues are not straight or clear-cut as Dr. Georgiou explains, “During the three years that I have been researching the efficacy of certain natural substances for their heavy metal chelating effects, I have stumbled across a few surprises. For example, the literature was full of testimonials on how chlorella and cilantro are excellent chelators of heavy metals, so we tested both of these in carefully designed, double-blind, placebo-controlled trials. Let’s take Chlorella vulgaris as an example—when we tested this alone in pre-post provocation urine and feces tests using 3,000 mg daily, we found no difference between the pre- and post-tests. In other words, chlorella by itself was not eliminating any metals that could be detected by an ICP-MS at parts per billion levels of measurement.”

Dr. George Georgiou and the Russian government invested one million dollars in a double-blind, placebo-controlled trial with 350 people that has shown that when natural substances are combined, they work as effectively as synthetic chelators. After much experimentation Georgiou selected cilantro, chlorella and a chlorella growth factor extract. The Mexicans eat a lot of cilantro and there are doctors there who have pioneered the use of this plant in detoxification and chelation protocols. It is important to remember the important point that medicinals work best in combination with others that are carefully selected and balanced in a formula and full protocol.

HMD (Heavy Metal Detox) from Dr. George Georgiou gives us, in my opinion, the best possible medical formula to help remove radioactive contamination. It is interesting to see that uranium-238 is being eliminated in the hair using the HMD protocol.

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If metals are present in the storage organs, then the probability is that you will get a dramatic INCREASE in the toxic metals compared to baseline – this indicates that the HMD™ is pulling heavy metals out of storage sites into the blood and then into the hair. This is a sure indication that the person has metals stored in the body and the clinical decision is to continue taking the HMD

Metal-Free

Another excellent chelator that works as part of a complete protocol, like the HMD does, is Metal-Free, which was designed and created by Dr. David Minkoff. He developed his unique chelation system to save his wife much the way Dr. Rashid Buttar developed his TD-DMPS to recover his son from autism. Dr. Minkoff wrote to me saying, “We have noticed for the past ten years an increasing number of patients with high uranium levels in the hair or on stool tests. Since uranium is one of the heaviest and densest metals, it behaves in the body as lead or mercury would with the added danger of radiation. I have no explanation for the increasing levels and have attributed them to the armor piercing weapons used in the Middle East and the fallout eventually coming back here and getting into the water and vegetation and then into people. We have even seen it in small infants. Metal-Free will increase the levels of uranium in the hair and stool after challenge which shows the increased excretion.” He stated this to me well before Fukushima happened!

The peptides in Metal-Free bind to heavy metals at several sites on the metal molecule rather than at one site. This creates a non-competitive irreversible bond. The peptide’s affinity to metal is strong, meaning that when a metal is picked up by Metal-Free it will not lose the particle along its way out of the body. Metals may be removed in the urine, sweat or fecal matter. Heavier metals, such as lead, mercury and uranium, are principally removed through the bowels, which mean the kidneys are protected from the heavy metals.

The cell receptor sites in the body have a lesser affinity to heavy metals as compared to Metal-Free. This means the locations in the body where metal is being stored will release this metal when the product pervades its area. When the metal is released from the receptor site, a molecule in the Metal-Free formula attaches itself onto the metal or toxin, which keeps it soluble and in circulation to be removed.

The formula attaches itself using all three methods of bonding (ionic, covalent and hydrogen) while DMPS uses only ionic. Metal-Free’s triple bond prevents the metal from being lost and reattaching itself into another area of the body. The peptides in Metal-Free are nanosized meaning they can easily penetrate skin and mucous membranes.

Stool levels for heavy metals using the Metal-Free formula are as follows:

Metal

Pre-challenge result (ppm)

Post-challenge result (ppm)

Increase

Reference Range (ppm)

Mercury

0.032

0.106

330%

< 0.05

Antimony

0.061

0.118

190%

< 0.08

Arsenic

3.87

6.6

170%

< 0.3

Beryllium

< dl

0.025

250%

< 0.009

Copper

40

300

750%

< 60

Nickel

8.3

18.6

220%

< 8

Uranium

0.066

0.302

450%

< 0.12

Dr. Minkoff said to me that, “Metal-Free, for reasons unknown and we have checked many times, does not bind beneficial minerals and so does not deplete the body while removing the heavy metals.” This is of course a problem when one uses synthetic chelators like DMPS. Metal-Free has been used by many doctors on thousands of patients as have all the chelation products I am presenting.

I present two different natural chelators that work with different principles because chelation is a long-term process and it behooves people to alternate and experiment with different types of natural chelators and to use them alternatively through the months and years. Using Edible or topical clay assists greatly in the chelation process.

Dr. Timothy Ray, an oriental medical doctor, speaks elegantly about avoiding the healing crisis that synthetic chelators so often bring. He has a product similar to HMD called NDF and NDF Plus that are based on chlorella and cilantro.

Mercury can also be bound to sulfhydryl groups
in garlic or to sulfur in the form of organic sulfur (MSM).

I have had the privilege of studying with many of these brilliant doctors. The first one was Dr. Alan Greenberg who created a stand-alone chelation formula named Chelorex. This is a good formula if you want an-everything-in-one-type product that contains a long list of appropriate and well-tested ingredients. Dr. Greenberg put his money where his mouth is and spent hundreds of thousands of dollars testing his formula and it showed very positive for uranium elimination as did the HMD.

Conclusion

I learned a lot from Dr. Greenberg and most of the items in his formula are in my protocol. Alpha Lipoic Acid (ALA) and N-acetyl cysteine (NAC)) did not make my top fifteen medicinals but would be next in my priority list. ALA is a serious chelator and should be taken with caution by starting at low dosages and supporting its use with a full protocol, which includes clay to make sure that the heavy metals do actually leave the body.

In the 21st century the center of pharmacology needs to be shifted
away from medicines that add to people’s already heavy toxic
burdens, to medicines and protocols that reduce these burdens.

Dr. Bert Berkson, who was licensed by the FDA to study the intravenous use of ALA, has had success even with some very difficult cancers. Dosages, though, have to hit the sweet spot to affect changes and cures. When it comes to concentrated nutritional medicine (Natural Allopathic Medicine) it is important to remember that we are using medicinals that are not poisonous (because the body needs them, that’s why we call them nutritional medicines). This means the operating medical principle is not the dose makes the poison (allopathic terrorism). It means that we can take the dosages up to the saturation point. With some medicinals like magnesium and vitamin C we have bowel tolerance levels to inform us when we reach this level. With sodium bicarbonate we have simple pH paper for a guidance system. With just about everything else we have plenty of medical science to guide us.

No matter what chelating method you use, they will all be more effective if your magnesium levels are not depleted. Magnesium is very important for phase one detoxification and it, along with other minerals like zinc, displaces toxic heavy metals from the body. Magnesium is a crucial factor in the natural self-cleansing and detoxification responses of the body. Thus it is reasonable to assume that low levels of magnesium would render a person or child vulnerable to heavy metal mobilization during chelation. Many of the problems with chelation can be reduced when a person is given sufficient magnesium. The therapeutic value of magnesium as a transdermal application reaches well beyond the potential of dietary magnesium or oral magnesium supplements. Transdermal therapy effectively saturates the tissues, delivering high amounts of magnesium directly into circulation.

Special Note: In a few weeks I will be publishing two video books, one to doctors and healthcare professionals of all stripes and another to patients called First Consultation. In them I will share my best guidance about dosages that in reality are a highly individual thing based on age, medical condition, sex, nutritional status, toxicity profile, and weight. Patients who are working without the guidance of a healthcare professional have to use feelings and feedback signals from the body. Intuition is also a feeling, as Einstein informed us, and the body is sensitive in terms of the feelings generated by substances taken-whether it is good for the body or not, and whether dosages are too high or too low.


[1] Radiat Res. 1986 Sep;107(3):296-306. Reducing the cancer risk of 239Pu by chelation therapy. Jones CW, Mays CW, Taylor GN, Lloyd RD, Packer SM.
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&
uid=3749464&cmd=showdetailview&indexed=google

[2] Journal of Advancement in Medicine Volume 2, Numbers 1/2, Spring/Summer 1989 Ninety Percent Reduction in Cancer Mortality after Chelation Therapy With EDTA Walter Blumer, M.D. and Elmer Cranton, M.D.

[4] The earliest types of chelation involved synthetic agents such as BAL, penicillamin e and EDTA administered intravenously for acute toxic metal poisoning. Subsequently, DMSA and DMPS were utilized, first intravenously and later orally and now even transdermally. Chelation therapy provides a relatively safe, effective, and inexpensive alternative to the drugs and surgery often used for circulatory disorders such as coronary heart disease, carotid (neck artery) stenosi (blockage), and leg artery stenosis (blockage). Chelation is a process by which toxic substances in the body, particularly heavy metals can be excreted safely. However, numerous negative side effects are associated with each of these chelators (with the exception of EDTA which is ‘relatively’ safe ) including allergic reactions involving the skin and mucous membranes (itching, exanthema or rash), as well as occasional cases of Stevens-Johnson Syndrome or erythema exudative multiforme.(11). Other side effects include nausea, headache, muscle aching, changes in taste, severe malaise, dizziness, numbness, insomnia, diarrhea, weight loss, extreme fatigue, leg cramps, cardiac arrhythmia, liver and kidney damage, abdominal pain, anxiety, severe restlessness, mental changes, tremors, inability to concentrate, poor memory, impaired equilibrium, chemical sensitivities and tinnitus. (12). Studies have shown up to 30% of patients have severe negative side effects as a result of these synthetic chelating agents, which may develop after a single dose. For warnings against DMPS all one has to do is go to the DMPS Backfire website.

[5] R. A. Goyer, M. G. Cherian, M. M. Jones, and J. R. Reigart. Role of Chelating Agents for Prrevention, Intervention, and Treatment of Exposures to Toxic Metals. Environmental Health Perspectives Volume 103, Number 11, November 1995